Comparative study of Fasting and postprandial dyslipidemia in Type2 DM

Type 2 Diabetes Mellitus (DM) is characterized by insulin resis­tance which is associated with glucose intolerance, hypertension, dyslipidaemia, a procoagulant state, and an increase in the mi­crovascular and the macrovascular disease. Diabetics are frequently hyperlipidemic and they are at a high risk for coronary heart disease. The high cardiovascular mortality which is as­sociated with Type 2 DM is due to a prolonged, exaggerated, postprandial state. The postprandial dysmetabolism and the associated oxidative stress may link the insulin resistance and the Type 2 DM to the disproportional incidence of cardiovascular disease. Postpran­dial hypertriglyceridaemia has been linked to asymptomatic and symptomatic macrovascular diseases in both normo or hy­pertriglyceridaemic subjects and such abnormalities have been reported in the type 2 diabetics. The increased risk of atheroscle­rosis among them, may therefore, be related to the higher post­prandial lipaemia in them. The postpran­dial dysmetabolism and the associated oxidative stress may link the insulin resistance and the Type 2 DM to the disproportional incidence of cardiovascular disease.

Dr. Suryabhan Lahanu Lokhande has passed M.B.B.S. from Indira Gandhi Government Medical College Nagpur in 2003 and completed M.D.(Biochemistry) from Government Medical College Nagpur in 2010 respectively. At present, He is working as Assistant Professor in the department of Biochemistry at Jawaharlal Nehru Medical College,Wardha; Maharashtra India.